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Discover Premium Acetonitrile (ACN) for Demanding Applications
Welcome to our dedicated product page for Acetonitrile (ACN). We supply high-purity Acetonitrile, a critical solvent for a wide range of industries, including pharmaceuticals, analytical laboratories, chemical synthesis, and more. Known for its excellent dissolving capabilities and unique chemical properties, ACN is an indispensable component in many advanced processes.
Our Acetonitrile is rigorously tested to ensure exceptional purity, making it ideal for sensitive applications such as High-Performance Liquid Chromatography (HPLC), gas chromatography, and DNA/RNA synthesis. With its low UV cut-off and low residue, our ACN helps you achieve reliable and reproducible results in your critical analyses and reactions.
What is Acetonitrile?
Acetonitrile (ACN), also known as methyl cyanide, cyanomethane, or ethanenitrile, is the simplest organic nitrile. It is a colorless liquid with a faint ether-like odor. Its chemical formula is C2H3N. As a primary solvent in many chemical and analytical applications, Acetonitrile is valued for its ability to dissolve a wide array of organic compounds, inorganic salts, and polymers. Its relatively low viscosity and boiling point make it easy to handle and remove from reactions.
It is produced as a byproduct of acrylonitrile manufacturing. Its industrial applications span from a solvent for rubber and plastic production to a raw material in the synthesis of pharmaceuticals, pesticides, and other organic chemicals. In the laboratory, it's a go-to solvent for a vast array of reactions and purification techniques.
| Acetonitrile Basic information | |
| Product Name | Acetonitrile |
| Synonyms | ACN, Cyanomethane, Ethyl nitrile, Methyl cyanide, Acetonitrile |
| CAS | 75-05-8 |
| Molecular Formula | C2H3N |
| Molecular Weight | 41.05 |
| EINECS | 200-835-2 |
| Acetonitrile Chemical Properties | |
| Melting point | -45 °C (lit.) |
| Boiling point | 81-82 °C (lit.) |
| Density | 0.786 g/mL at 25 °C (lit.) |
| Storage temp | Store at +5°C to +30°C. |
| Solubility | Organic solvents: soluble(lit.) |
| Form | Liquid |
| pka | 25(at 25℃) |
| Specific Gravity | approximate 0.78(20/20℃) |
| Odor | Aromatic ether-like odor detectable at 40 ppm |
| Refractive Index | 0.46 |
| Water Solubility | Miscible |
| Acetonitrile Safety Information | |
| Hazard Codes | F,Xi,Xn,T |
| Risk Statements | 11-36-20/21/22-10-36/37/38-23/24/25-41-24-20/22 |
| Safety Statements | 16-36/37-45-36/37/39-27-26-36 |
| RIDADR | UN 1993 3/PG 3 |
| WGK Germany | 2 |
| RTECS | AL7700000 |
| Hazard Class | 3 |
| Packing Group | II |
Is Acetonitrile Polar? Understanding Its Polarity
Yes, Acetonitrile is a polar solvent. It possesses a significant dipole moment due to the highly electronegative nitrogen atom in the nitrile group (–C≡N). This strong polarity allows it to dissolve both polar and some non-polar compounds. More specifically, Acetonitrile is classified as a polar aprotic solvent.
Polar: It has an uneven distribution of electron density, leading to a partial positive charge on the carbon atom and a partial negative charge on the nitrogen atom in the nitrile group.
Aprotic: Unlike solvents such as water or alcohols, Acetonitrile does not have hydrogen atoms directly bonded to highly electronegative atoms (like oxygen or nitrogen) that can participate in hydrogen bonding as proton donors. This characteristic makes it an excellent choice for reactions that are sensitive to proton donation.
Its polarity combined with its aprotic nature makes Acetonitrile highly versatile and indispensable in many chemical syntheses and analytical separations, particularly in HPLC, where it is frequently used as a mobile phase component due to its solvent strength and compatibility with various detectors.
Key Features & Applications of Our Acetonitrile:
High Purity: Ensured for critical applications like HPLC and spectroscopy, minimizing interference.
Excellent Solvent Properties: Dissolves a broad range of organic and inorganic compounds.
Low UV Cut-off: Ideal for UV-sensitive detectors in chromatography.
Low Residue: Minimizes non-volatile impurities, crucial for analytical accuracy.
Versatile Applications:
High-Performance Liquid Chromatography (HPLC): As a mobile phase component for analytical and preparative separations.
Organic Synthesis: A favored solvent for various reactions.
Extraction: Used in the extraction of fatty acids, vegetable oils, and other compounds.
Spectroscopy: Solvent for UV/Vis, NMR, and IR spectroscopy.
DNA/RNA Synthesis: Essential for oligonucleotide synthesis.
Battery Applications: Used in lithium-ion batteries as a component of the electrolyte.
Order High-Purity Acetonitrile Today
Ready to enhance your laboratory or industrial processes with high-quality Acetonitrile? Contact us to discuss your requirements, request a quote, or place an order. Our team is ready to provide you with the best solvent solutions tailored to your needs.
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